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KMID : 0385520080210050345
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Analytical Science & Technology
2008 Volume.21 No. 5 p.345 ~ p.363
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Process analytical technology (PAT): new paradigm for the state-of-the-art analytical technology
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Kim Jong-Yun
Park Yong-Joon
Yeon Jei-Won
Woo Young-Ah
Kim Hyo-Jin
Song Kyu-Seok
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Abstract
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Process analytics has been already widely utilized in a large-scale continuous production line such as petroleum industries for several decades. Although the process analytics has a long history, a concept of “Process Analytical Technology (PAT)” has been rapidly adopted as a new paradigm for the process monitoring in the production process of various industries. In this review, current status and recent developments of PAT in various research bodies have been introduced, including the introduction of various types of analytical instruments, chemometrics tools, and perspectives and future applications of PAT as well as the fundamentals on PAT such as terminology and its historical background.
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KEYWORD
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Process analytical technology, process analytical chemistry, chemometrics, design of experiment, proces
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